In this context, DP (= end-inspiratory pressure minus EIP both at zero flow) has the advantage to take into consideration lung compliance that is related to the effective size of aerated lung at the end of expiration ( 4, 5). The exact levels of pressures and volumes that are safe have been discussed and depend probably importantly on the underlying pulmonary condition ( 3). On the other hand, there is evidence that low tidal volumes (V T) ( 1), and low driving (DP) ( 2), and end-inspiratory plateau (EIP) ( 1) pressures improve outcome. Therefore, the patient’s physiological reserve and tolerance to hypoxemia and hypercapnia have to be taken into account when deciding the individually acceptable PaO 2 and PCO 2, and these acceptable levels could change during the disease process. However, there are no definite safe levels of PaO 2 and PaCO 2. Exhaled gas and blood gas analysis monitor gas exchange, whereas lung mechanics (pressures, volumes and flow) and lung imaging enable the clinician to make sure they provide with lung protective ventilation as much as possible. The purpose of lung ventilation is providing adequate gas exchange without inducing further injuries to the lungs and other organs. Keywords: Acute respiratory distress syndrome (ARDS) monitering gas exchange lung mechanics lung imaging Policy of Dealing with Allegations of Research Misconduct.Policy of Screening for Plagiarism Process.
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